Insight Resource Library Tap into Gubra’s vast production of publications, webinars, videos and posters to get the latest knowledge and insights within our focus areas: obesity, diabetes, MASH, CKD, IPF and IBD. 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therapeutic effects of the dual FXR/TGR5 agonist INT-767 in the GAN diet-induced ob/ob mouse model of advanced MASH with progressive fibrosis PosterClinical translatability of the GAN diet-induced obese and biopsy-confirmed mouse model of MASH WebinarWhole organ staining and 3D light sheet imaging for pharmacological research PublicationIdentification of GDF15 peptide fragments inhibiting GFRAL receptor signaling WebinarUsing whole brain imaging for development of obesity drugs PosterPreclinical efficacy and clinical translatability of obeticholic acid in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH PosterWhole Brain cFos Response to Different Amylin Receptor Agonists PublicationLEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men PosterMetabolic, biochemical and histological effects of INT-767 in the GAN diet-induced and biopsy-confirmed ob/ob mouse model of NASH PublicationDigital brain maps and virtual neuroscience. An emerging role for light sheet fluorescence microscopy in drug development PublicationLipidated PrRP31 metabolites are long acting dual GPR10 and NPFF2 receptor agonists with potent body weight lowering effect PosterCombinations of an Acetyl Coenzyme-A Carboxylase Inhibitor, FXR Agonist, and GLP-1R Agonist Inhibit Fibrosis Progression in the Rat Choline-Deficient, L-Amino-Acid–Defined, High-Fat Diet Model of Advanced Fibrosis PublicationAn aldehyde responsive, cleavable linker for glucose responsive insulins PublicationIdentification and metabolic profiling of a novel human gut-derived LEAP2 fragment PublicationRodent models of diabetic kidney disease: human translatability and preclinical validity PosterObeticholic acid improves histological, biochemical and gene expression profiles in Gubra AMLN mice with diet-induced and biopsy-confirmed NASH PublicationValidity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH PublicationHalf-Life extending modifications of peptide YY3-36 direct receptor-mediated internalization PublicationCombined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH PublicationAnimal models of type 2 diabetes, obesity and nonalcoholic steatohepatitis – clinical translatability and applicability in preclinical drug development PublicationDisease progression and pharmacological intervention in a nutrient-deficient rat model of nonalcoholic steatohepatitis Load More For further information Contact us Gubra Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 2650