Cro services in
Intestine (IBD)
Gubra is frontrunner in preclinical models of inflammatory bowel disease (IBD) with intestinal fibrosis. Explore your IBD-targeted drug for anti-inflammatory and anti-fibrotic efficacy in our chronic dextran sulfate sodium (DSS) model of IBD.
Why Gubra?
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Expert scientific guidance within IBD
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State-of-the art chronic IBD-fibrosis model
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AI-powered histological analysis
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Tailored study design and rapid initiation
Consult with Michael Feigh
Vice President, Scientific Sales
Reach out to our experts to learn how we can move your IBD drug pipeline forward.
Advance your IBD program by exploring immune and fibrosis endpoints
Gubra provides state-of-the-art DSS mouse models for IBD prevention and intervention studies. We use advanced AI-based histological techniques to determine therapeutic effects on disease hallmarks. Explore our novel chronic DSS-IBD mouse model with progressive colonic fibrosis.
Main Offerings
Biochemical assessment
Colon and plasma
Colon stereological
quantification
Histopathological scoring
Inflammation & fibrosis
Quantitative histology
Inflammation & fibrosis
Colon transcriptomic
profiles
Inflammatory bowel disease (IBD) Models
Acute DSS-IBD mouse
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Chow-fed C57BL/6J mice
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Standard model of acute ulcerative/inflammatory colitis
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Rapid onset of colon-specific mucosal epithelial injury
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Short lead-in time for study initiation
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Stereology-based histopathological analysis
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Advanced transcriptomics profiling
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Prophylactic treatment
Chronic DSS-IBD mouse
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Chow-fed C57BL/6J mice
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Long-term (cyclic) DSS administration
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State-of-the-art model of chronic IBD with fibrosis
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Stereology-based histopathological analysis
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Advanced transcriptomics profiling
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Treatment intervention
Related pages
For further information
Contact us
Gubra
Hørsholm Kongevej 11B
2970 Hørsholm
Denmark
+45 3152 2650