Technologies in
Histology
We make histology into clear interpretable data. Gubra is a leading CRO specialized in histology services using AI-assisted quantification of disease markers and therapeutic endpoints. Our full-range histology service is fully integrated with our in vivo platform to ensure efficient, complete and high-quality evaluation of study endpoints.
Why Gubra?
- Expert histology solutions
- Clinical endpoints to ensure translatability
- Histopathology hallmark stainings
- High‐throughput multiplex stainings
- AI-assisted quantitative histology
- AI-enabled unbiased histopathological scoring
- Unbiased stereology-based quantitative histology
Consult with Marco Tozzi
Research Scientist, Scientific Sales
Find out how histology can be tailored to map targets and therapeutic effects of your drug.
Complete and high-quality histology analysis can move your drug pipeline forward
High-quality histology is essential in preclinical drug development to understand its mode of action. We offer routine and advanced histology services, including core histology, multiplex immunohistochemistry, RNAScope®, as well as unbiased stereology analysis for best-practice whole-sample quantitative histology.
Main Offerings
Multiplexed IHC &
ISH endpoints
AI-based
histopathological scoring
Quantitative
Histology
Unbiased stereological
quantification
Applicable to
all organs
clear interpretable data
Histology Solutions
Immunohistochemistry (IHC)
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Chromogen- or fluorescence-based IHC
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Single, dual or multiplex stainings
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AI-assisted mapping and quantification
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Compatible with light sheet-processed samples
In Situ Hybridization (ISH)
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Chromogen- or fluorescence-based ISH
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Single, dual or multiplex ISH
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Specializing in RNAScope® ISH
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AI-assisted mapping and quantification
Histochemical Stains
- Histopathology hallmark stainings
- AI-enabled unbiased histopathological scoring
- Quantitative morphometrics derived from scoring variables
- Hematoxylin-eosin (HE)
- Picrosirius red (PSR)
- Periodic Acid-Schiff (PAS)
Image Analyses
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High-throughput 2D imaging
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Automated AI-based quantitative histology platforms
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Gubra-AI (GHOST) unbiased histopathological scoring
Stereology
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Expert unbiased stereological quantification
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Applicable to any organ and histological endpoint
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Definitive method for 2D-based whole-sample analysis
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Optimized pipeline for efficient and fast analysis
Laser Capture Microdissection (LCM)
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Isolation of staining-positive cells from tissue sections
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Harvesting of cells under direct microscopic visualization
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RNAseq for identifying cell-type specific gene regulations
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Applicable to any organ of interest
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Highly instrumental in target discovery
Custom Services
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Reach out to our histology experts to learn how we can provide histological solutions tailored to your specific research needs
Related pages
For further information
Contact us
Gubra
Hørsholm Kongevej 11B
2970 Hørsholm
Denmark
+45 3152 2650