Technologies in
Histology
We make histology into clear interpretable data. Gubra is a leading CRO specialized in histology services using AI-assisted quantification of disease markers and therapeutic endpoints. Our full-range histology service is fully integrated with our in vivo platform to ensure efficient, complete and high-quality evaluation of study endpoints.
Why Gubra?
- Expert histology solutions
- Clinical endpoints to ensure translatability
- Histopathology hallmark stainings
- High‐throughput multiplex stainings
- AI-assisted quantitative histology
- AI-enabled unbiased histopathological scoring
Consult with Allison Butt
Senior Scientist, Scientific Sales
Get more information on our high troughput histology services.
Complete and high-quality histology analysis can move your drug pipeline forward
High-quality histology is essential in preclinical drug development to understand its mode of action. We offer routine and advanced histology services, including core histology, immunohistochemistry, multiplex immunofluorescence and RNAScope®. We offer a fully digitalized process with machine learning and deep learning-based image analysis together with high throughput python-based image analysis pipelines.
Main Offerings
Multiplexed IHC &
ISH endpoints
AI-based
histopathological scoring
Quantitative
Histology
Applicable to
all organs
Whole slide imaging (WSI) and digitial pathology
clear interpretable data
Histology Solutions
Histology and histopathology
- Specialized histochemical stains for a range of morphological structures
- Paraffin embedding & frozen tissue processing and sectioning
- Histopathological evaluation
- AI-enabled unbiased histopathological scoring and image analysis
Immunohistochemistry and immunofluorescence
- Reproducible and automated techniques
- High troughput automated staining (Dako48®)
- Optimized methods for a broad array of markers
- Protocol optimization
- Paraffin & frozen tissue samples
- Single & multiplex stainingCompatible with light sheet processed samples
In situ hybridization (RNAscope®)
- Reproducible and automated techniques (LeicaBondRX®)
- Chromogen & fluorescent detection
Single and multiplex staining - Combined with IHC-RNAScope®
- Customized probes and protocols
- Paraffin & frozen tissue samples
Digital image analysis
- Machine learning and deep learning-based image analysis (Visiopharm®)
- High throughput python-based image analysis pipelines
- Readouts for both quantity and location in tissue
- Reproducible and fast readouts
Digital pathology
- High resolution scanning (Aperio GT450® )
- High throughput analysis of whole slides images
- AI-based histopathological scoring
- Global costumer access via cloud based image sharing
Custom Services
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Reach out to our histology experts to learn how we can provide histological solutions tailored to your specific research needs
Related pages
For further information