Cro services in
Diabetes
At Gubra we have decades of scientific expertise in conducting preclinical studies using animal models of type 2 diabetes. We can provide end-to-end study design, and comprehensive data combining in vivo metabolic profiling with hormonal analysis, histology and RNAseq to evaluate the impact of your anti-diabetic drug candidate.
Why choose Gubra?
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Expert scientific guidance within diabetes
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Extensive experience in anti-diabetic drug profiling
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Golden standard type 2 diabetic rodent models
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Tailored study design and rapid initiation
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Combination of pharmacology and histology

Consult with Marco Tozzi
Principal Scientist, Scientific Sales
Advance your diabetes drug development with our extensive knowhow.
Decades of experience in anti-diabetes drug profiling
We have extensive knowhow in conducting preclinical studies using animal models of type 2 diabetes. Our technical expertise includes working with difficult models such as ZDF rats or db/db mice as well as quantifying beta-cell mass and other histological-pathological endpoints of diabetes.
Main Offerings
Diabetic rodent models
Treatment efficacy studies
Full metabolic
assessment services
Glucose homeostasis
evaluation
Insulin sensitivity testing
Islets and β-cells
quantification
We work with the common models of diabetes
Models of Diabetes

db/db mouse
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Deficient leptin receptor signalling
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Morbid obesity and impaired glucose tolerance
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Early phenotype of type 2 diabetes
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Well-defined progression in islet pathology
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Suitable for treatment intervention
- Validated with several anti-diabetic drug classes

ZDF rat
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Deficient leptin receptor signalling
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Morbid obesity and impaired glucose tolerance
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Early phenotype of type 2 diabetes
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Well-defined progression in islet pathology
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Suitable for treatment intervention
- Validated with several anti-diabetic drug classes
Cloud-based data viewer
GubraView
Our cloud-based data viewer GubraView provides instant access to study data as it is uploaded, ensuring seamless monitoring throughout your study. With features for cross-group and cross-study comparisons, GubraView enables informed decision-making with statistical analyses. Accessible across multiple locations, GubraView empowers efficient and collaborative drug development for your whole team.

Related pages
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