Contract research services within obesity

We have conducted preclinical obesity studies in the vast majority of all commercially available rodent models. One of our hallmarks is the ability to measure food preference changes in a diet-induced obese (DIO) rat model.

Our 15 years scientific and technical CRO expertise combined with a constant animal availability and readiness translate into speed and high scientific standards. We provide solid data and scientific guidance, which you can use as the foundation for business decisions moving your projects forward.

We offer:

• DIO models and the majority of commercially available models
• Acute or chronic anorectic properties assessed in real-time food/water/activity system
• Monitoring of food preference, taste aversion and pica behavior
• Site-specific compound administration, e.g. intrathecal, intracerebroventricular or local injections into specific nuclei in the brain
• Total body fat measurements using our EchoMRI scanner
• Tissue fat measurements using small sample EchoMRI scanner
• Energy expenditure testing using indirect calorimetry
• In vivo lipogenesis
• Selective vagal deafferentiation and other MoA validations
• RNA sequencing and bioinformatics