Preclinical ovary histology: AI-assisted analysis of reproductive tissue and endpoints
Explore how we perform estrous cycling to determine the estrous cycle stage of our women’s health animal models.
Supporting next-generation Alzheimer’s disease research with quantitative whole-brain imaging
With whole-brain spatial imaging, teams can move from selected sections to atlas-aligned, brain-wide endpoints that support more confident decisions in neurodegenerative disease research.
Understanding the blood-brain barrier: Function, structure, and role in CNS drug delivery
Explore how Gubra supports preclinical BBB studies that integrate CNS drug delivery with spatial characterization of disease biology.
AI-based lung histology in preclinical IPF models: Bridging preclinical and clinical insight
Explore how AI-driven image analysis can enhance the evaluation of complex lung pathology and support more precise, quantitative readouts in fibrosis research.
AI-based scoring and quantitative image analysis in preclinical kidney disease models
In this article, we explore how AI-based scoring and quantitative image analysis are advancing preclinical kidney pathology.
Quantifying neurodegenerative disease with 3D Imaging: A new standard in preclinical CNS research
The challenge of accurately quantifying neurodegeneration in preclinical models Neurodegenerative disease is a spatially distributed, circuit-level process rather than a focal pathology. In Alzheimer’s disease (AD) mouse models, amyloid-β (Aβ) pathology and neuroinflammation extend across cortical and hippocampal regions. In…
What is in vivo pharmacology?
What is in vivo pharmacology, and why is it essential in drug development? This article explains how in vivo pharmacology studies support preclinical research,
Liver histology in preclinical models: AI-powered analysis for translational research
Preclinical histology work can greatly accelerate drug development and IND filings for final FDA approval. Read more about Gubra's preclinical histology services here.
FDA approves semaglutide (Wegovy®) for MASH: What does this mean for drug development and preclinical innovation?
As the drug development landscape evolves, the need for reliable and translational preclinical MASH models has never been greater.
Which IPF model offers the highest translational relevance in preclinical research?
The development of effective therapies for Idiopathic Pulmonary Fibrosis (IPF) relies fundamentally on selecting the appropriate in vivo preclinical mouse model. While the bleomycin model remains the cornerstone of preclinical research services, achieving maximal clinical relevance is not about finding…