Insight Resource Library Tap into Gubra’s vast production of publications, webinars, videos and posters to get the latest knowledge and insights within our focus areas: obesity, diabetes, MASH, CKD, IPF and IBD. 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combination treatment of obese-diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries PublicationTherapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease PublicationCharacterization of local gut microbiome and intestinal transcriptome responses to rosiglitazone treatment in db/db mice Publication3D quantification of changes in pancreatic islets in mouse models of diabetes type I and II PublicationAutomated image analyses of glomerular hypertrophy in a mouse model of diabetic nephropathy PublicationImpact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice PublicationRhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones PublicationAnimal models of type 2 diabetes, obesity and nonalcoholic steatohepatitis – clinical translatability and applicability in preclinical drug development PublicationPancreatic β-cell rest replenishes insulin secretory capacity and attenuates diabetes in an extreme model of obese type 2 diabetes PublicationNovel GLP-1/GLP-2 co-agonists display marked effects on gut volume and improves glycemic control in mice PublicationGUB06-046, a novel secretin/glucagon-like peptide 1 co-agonist, decreases food intake, improves glycemic control, and preserves beta cell mass in diabetic mice PublicationNeoglycolipids for prolonging the effects of peptides: Self-assembling glucagon-like peptide 1 analogues with albumin binding properties and potent in vivo efficacy PublicationRobust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates PublicationThe novel GLP-1-gastrin dual agonist ZP3022 improves glucose homeostasis and increases β-cell mass without affecting islet number in db/db mice PublicationCharacterisation of age-dependent beta cell dynamics in the male db/db mice PublicationThe imprinted gene neuronatin is regulated by metabolic status and associated with obesity For further information Contact us Gubra Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 2650