Skip to content

Lost in translation – how to improve the translatability of rodent models of diabetic kidney disease

Senior scientist Mette Viberg Østergaard introduces to the challenges of using current rodent models of diabetic kidney disease in drug discovery and development. Mette then presents an example of how translatability may be improved in a model of diabetic kidney disease in the setting of type 2 diabetes and hypertension.

3D imagingAdeno-associated virus (AAV)-mediated gene deliveryChronic kidney diseaseReninAAV UNx db/db mouseMouseBody weightBlood biochemistryDiabetic kidney diseaseImage analysisImmunohistochemistry (IHC)Kidney morphometryNext-generation sequencingNephrectomyUrine biochemistry

For further information

Contact us


Hørsholm Kongevej 11B
2970 Hørsholm

+45 3152 ­2650

Back To Top