Nephroprotective effects of semaglutide in a preclinical model of hypertensive diabetic kidney disease
In this webinar, Gubra’s experts on preclinical DKD models, Principal Scientists Mette Østergaard and Henrik Björk Hansen, will discuss the effects of semaglutide on renal functional, histological and gene expression markers of advanced DKD in the db/db UNx-ReninAAV mouse.
Lost in translation – how to improve the translatability of rodent models of diabetic kidney disease
Senior scientist Mette Viberg Østergaard introduces to the challenges of using current rodent models of diabetic kidney disease in drug discovery and development. Mette then presents an example of how translatability may be improved in a model of diabetic kidney disease in…
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
American Journal of Physiology-Renal Physiology 321(2):F149-F161, 2021
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy
Scientific Reports 10:16130, 2020
Automated image analyses of glomerular hypertrophy in a mouse model of diabetic nephropathy
Kidney360 1(6): 469-479, 2020