Nephroprotective effects of semaglutide in a preclinical model of hypertensive diabetic kidney disease
In this webinar, Gubra’s experts on preclinical DKD models, Principal Scientists Mette Østergaard and Henrik Björk Hansen, will discuss the effects of semaglutide on renal functional, histological and gene expression markers of advanced DKD in the db/db UNx-ReninAAV mouse.
Lost in translation – how to improve the translatability of rodent models of diabetic kidney disease
Senior scientist Mette Viberg Østergaard introduces to the challenges of using current rodent models of diabetic kidney disease in drug discovery and development. Mette then presents an example of how translatability may be improved in a model of diabetic kidney disease in…
Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease
Disease Models & Mechanisms 14(10): dmm049086, 2021
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
American Journal of Physiology-Renal Physiology 321(2):F149-F161, 2021