Gubra Services

We offer highly specialized services within the following disease areas and technologies.

Gubra Services

Liver (NASH)

Benefit from our extensive know-how in NASH and test your compound in our validated DIO NASH mouse models.

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Kidney

Check out our novel rodent models of diabetic nephropathy.

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3D Imaging

Use quantitative light-sheet fluoresence microscopy to validate pre-clinical endpoints.

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Obesity

Tap into our vast scientific experience with diet-induced obesity (DIO) models and other commercially available models.

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Heart (CVD)

Check out our novel rodent models of cardiovascular disease.

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Brain

Check out our capabilities in neurodegenerative diseases.

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Diabetes

Qualify and advance your assessment of novel compounds to treat type 2 diabetes and diabetic complications.

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Lung (IPF)

Check out our services within lung diseases.

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Gubra imaging services across indications

Get the full picture

Using quantitative 3D light sheet microscopy, you can assess drug efficacy and drug distribution in a whole new way. The results that you get are absolute and can be easily accessed in our dataviewer GubraView.

With our interactive brain browser (Gubra 3D Explorer) you can explore individual brain regions of interest, display quantitative c-Fos data and filter for regions with statistical significant response to drug treatment. 

Related links:

Whole-brain activation signatures of weight-lowering drugs

Our paper on whole-brain 3D activation signatures on six different weight-lowering compounds is featured on the front cover of Molecular Metabolism (Vol 47 – May 2021). 

Download paper: Whole-brain activation signatures of weight-lowering drugs