Gubra Services
We offer highly specialized services within the following disease areas and technologies.
Gubra Services
Benefit from our extensive know-how in NASH and test your compound in our validated DIO NASH mouse models.
Learn moreUse quantitative light-sheet fluoresence microscopy to validate pre-clinical endpoints.
Learn moreTap into our vast scientific experience with diet-induced obesity (DIO) models and other commercially available models.
Learn moreQualify and advance your assessment of novel compounds to treat type 2 diabetes and diabetic complications.
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Gubra imaging services across indications
Get the full picture
Using quantitative 3D light sheet microscopy, you can assess drug efficacy and drug distribution in a whole new way. The results that you get are absolute and can be easily accessed in our dataviewer GubraView.
With our interactive brain browser (Gubra 3D Explorer) you can explore individual brain regions of interest, display quantitative c-Fos data and filter for regions with statistical significant response to drug treatment.
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Whole-brain activation signatures of weight-lowering drugs
Our paper on whole-brain 3D activation signatures on six different weight-lowering compounds is featured on the front cover of Molecular Metabolism (Vol 47 – May 2021).
Download paper: Whole-brain activation signatures of weight-lowering drugs