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Filtered (40) Filters Reset all × A3907 × Dietary intervention × Rat × Search × Resource type Data presentation (0) Poster (8) Publication (30) 3D imaging video (0) Webinar (2) Category × Disease model (222) Cardiovascular disease (11) AngII mouse (2) DIO-ApoE-KO mouse (1) DIO-LDLR-KO mouse (4) DIO-PCK9-AAV mouse (1) Isoprenaline-induced cardiomyopathy (1) Cholangiopathy (1) Bile duct ligation (BDL) mouse (1) Mdr2-KO mouse (1) CNS disease (39) Alzheimer's disease models (9) CNS activation (12) Drug distribution (6) Gene expression (1) Gene therapy (1) Parkinson's disease models (6) Diabetes (33) db/db mouse (17) Non-obese diabetic (NOD) mouse (4) ZDF rat (10) Inflammatory bowel disease (3) Acute DSS-IBD mouse (0) Chronic DSS-IBD mouse (3) Idiopathic pulmonary fibrosis (7) BLEO-IPF mouse (4) Chronic BLEO-IPF mouse (2) HFD-BLEO-IPF mouse (0) Kidney disease (33) Acute kidney injury (4) Bilateral ischemia reperfusion injury (bIRI) mouse (1) Unilateral ischemia reperfusion injury (uIRI) 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surgical rat model of progressive chronic kidney disease and kidney failure PosterAutomated AI-assisted assessment of NAS and fibrosis stage in biopsy-confirmed rodent models of MASH PublicationDietary intervention reverses molecular markers of hepatocellular senescence in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH PosterThe autotaxin inhibitor BLD-0409 improves disease hallmarks in the CDAA-HFD-induced non-obese and biopsy-confirmed rat model of NASH with progressive fibrosis PosterAI-assisted Gubra Histopathological Objective Scoring Technique (GHOST) for unbiased, fast and accurate assessment of disease severity in rodent models of NASH WebinarWhole organ staining and 3D light sheet imaging for pharmacological research PublicationA3907, a systemic ASBT inhibitor, improves cholestasis in mice by multi-organ activity and shows translational relevance to humans WebinarApplications of advanced transcriptomics in preclinical research PosterCharacterization of dietary intervention in the non-obese CDAA-HFD mouse model of advanced NASH with progressive fibrosis PublicationStructurally-engineered fatty acid 1024 (SEFA-1024) improves diet-induced obesity, insulin resistance, and fatty liver disease PosterMetabolic, biochemical, histopathological, and transcriptomic effects of dietary intervention in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH PublicationDigital brain maps and virtual neuroscience. An emerging role for light sheet fluorescence microscopy in drug development PublicationHepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH PosterA3907, a novel inhibitor of bile acid transport in the intestine and the kidney, improves markers of metabolic and hepatic pathology and reduces NAFLD activity score and fibrosis stage in a diet-induced and biopsy-confirmed mouse model of nonalcoholic steatohepatitis PublicationTranscriptomic changes in pancreatic islets, adipose and liver after Roux-en-Y gastric bypass in a diet-induced obese rat model PublicationRat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy PublicationRodent models of diabetic kidney disease: human translatability and preclinical validity PublicationThe dorsomedial hypothalamus and nucleus of the solitary tract as key regulators in a rat model of chronic obesity PublicationGlobal transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss PublicationThe preprohormone expression profile of enteroendocrine cells following Roux-en-Y gastric bypass in rats PublicationExperimental non-alcoholic steatohepatitis in Göttingen Minipigs: consequences of high fat-fructose-cholesterol diet and diabetes PublicationAnimal models of type 2 diabetes, obesity and nonalcoholic steatohepatitis – clinical translatability and applicability in preclinical drug development Load More For further information Contact us Gubra Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 2650