Publication
Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy
Scientific Reports 10:16130, 2020
Thisted L, Østergaard MV, Pedersen AA, Pedersen PJ, Lindsay RT, Murray AJ, Fink LN, Pedersen TX, Secher T, Johansen TT, Thrane ST, Skarsfeldt T, Jelsing J, Thomsen MB, Zois NE
Therapeutic AreaCardiovascular disease (CVD)Chronic kidney disease (CKD)Beta-cell massIsoprenaline-induced cardiomyopathyMethod/EndpointSpeciesDiabetesBody weightRatDiabetic cardiomyopathyBlood biochemistryDiabetic kidney disease (DKD)BioinformaticsEchocardiography (ECG)Glomerular filtration rate (GFR)Image analysisImmunohistochemistryKidney morphometryNephrectomyPancreatectomyRNA sequencingSurgeryUrine biochemistry
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