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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

Nature Communications 15(1):1192, 2024. Lund C, Ranea-Robles P, Falk S, Rausch DM, Skovbjerg G, Vibe-Petersen VK, Krauth N, Skytte JL, Vana V, Roostalu U, Pers TH, Lund J, Clemmensen C.

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3D imaging DIO mouse Mouse Obesity models Bioinformatics Obesity FGF receptor-1 FGF21 Image analysis Immunohistochemistry MC4 receptor Light sheet fluorescence microscopy (LSFM)Vasculature

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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

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