Publication
Activation of adenosine monophosphate-activated protein kinase reduces the onset of diet-induced hepatocellular carcinoma in mice
Hepatology Communications 4(7):1056-1072, 2020
Schmoll D, Ziegler N, Viollet B, Foretz M, Even PC, Azzout-Marniche D, Madsen AN, Illemann M, Egebjerg KM, Feigh M, Czech J, Glombik H, Olsen JA, Hennerici W, Steinmeyer K, Elvert R, Castañeda TR, Kannt A
Therapeutic AreaGAN DIO-MASH-HCC mouseMouseTargetob/ob mouseMethod/EndpointSpeciesAMPKAMLN ob/ob-MASH mouseBody weightBlood biochemistryHepatocellular carcinomaMetabolic dysfunction-associated steatohepatitisHistopathology scoreImage analysisImmunohistochemistry (IHC)Liver biopsyLiver morphometryReal-time food intake/activity analysis
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