HØRSHOLM, Denmark – March 6, 2020
Congratulations to Gubra and PhD student Mathias Bonde Møllerhøj (MSc). We just received a co-financed industrial PhD scholarship from the Danish Diabetes Academy for Mathias’ research project “Identification and validation of fibrosis targets in non-alcoholic steatohepatitis”.
In collaboration with clinical expert Professor Lise Lotte Gluud at the Department of Clinical Medicine, Hvidovre Hospital, Mathias will investigate gene profiles from hundreds of clinical and preclinical liver samples. The project will give us a deeper understanding of the molecular mechanisms involved in the development of fibrosis in non-alcoholic steatohepatitis (NASH) and identify and validate new drug candidates for the treatment of NASH.
Worldwide, an increase of non-alcoholic fatty liver disease (NAFLD) is observed and it is estimated that approx. 25% of the population in the western world has fatty liver. NAFLD is a complex spectrum of liver diseases ranging from benign hepatic steatosis to the more aggressive necroinflammatory manifestation, NASH. NASH can lead to cirrhosis, hepatocellular carcinoma, and hepatic failure. Currently, liver transplantation is the only option for NASH cirrhosis. There are no approved drugs to treat NASH yet.
Sofia Pitt Boserup
Lead Communication Partner
Gubra is a privately held biotech company since 2008, headquartered in Denmark. The company is a science and technology driven company with two primary areas of business: Preclinical contract research services (CRO) and proprietary early target and drug discovery programs. Gubra’s primary focus is within the metabolic space (obesity, diabetes, NASH, CKD, CVD and diabetic complications) adding to this fibrotic disease areas such as IPF and IBD. Gubra specializes in in vivo pharmacology, peptide chemistry, molecular pharmacology, histology, 3D imaging, stereology, NGS (next generation sequencing), bioinformatics and ex vivo assays. High quality, scientific excellence, advanced digitalization, speed and solid teamwork, are key company traits which have established Gubra as a highly professional and competent partner in the market. Learn more at www.gubra.dk