Streamlined path from preclinical to clinical stage

Explore our industry-leading translational models of MASH & MASH-HCC

Gubra’s GAN DIO-MASH model has been top-ranked by LITMUS consortium for its human proximity score and clinical translatability. Explore our entire model portfolio to ensure a successful preclinical study and smooth transition to the clinical stage.

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Meet us at the AASLD 2024

Download Gubra’s AASLD Posters

We are attending AASLD The Liver Meeting from November 14-19, 2024. You can download our posters and explore the clinical translatability of our GAN DIO-MASH model, as well as our other biopsy-confirmed models for MASH and MASH-driven HCC.

Hepatoprotective effects of longer-term treatment intervention with Semaglutide and Tirzepatide in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH
Abstract no: 1101
Presentation: 2024-11-15
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Reproducible hepatoprotective effects and clinical translatability of semaglutide in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH

Abstract no: 1089
Presentation: 2024-11-15

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Reproducible hepatoprotective effects and clinical translatability of resmetirom in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH
Abstract no: 1090
Presentation: 2024-11-15
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Additive hepatoprotective effects of semaglutide and resmetirom combination therapy in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH
Abstract no: 1102
Presentation: 2024-11-15
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Dietary intervention improves intestinal permeability and reduces colonic fibro-inflammation in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH 
Abstract no: 2265
Presentation: 2024-11-16
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Standard Study Outlines

1. GAN DIO-MASH mouse model

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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2. GAN DIO-MASH-HCC mouse model

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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3. GAN ob/ob-MASH mouse model (prophylactic)​

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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4. GAN ob/ob-MASH mouse model (therapeutic)​

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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5. CDAA-HFD mouse​ model

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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6. CDAA-HFD rat model

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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We are experts in bridging preclinical and clinical development.

MICHAEL FEIGH Vice President, Scientific Sales

Michael’s primary focus is on MASH, MASH-HCC, obesity and idiopathic pulmonary fibrosis (IPF). Michael provides customers with scientific expertise in metabolic and fibrotic diseases, and knowhow for the preclinical evaluation of drug candidates from discovery to IND-enabling.

Let’s meet at the EASL 2024

Contact us

Gubra

Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 ­2650

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