Streamlined path from preclinical to clinical stage

Explore our industry-leading translational models of MASH & MASH-HCC

Gubra’s GAN DIO-MASH model has been top-ranked by LITMUS consortium for its human proximity score and clinical translatability. Explore our entire model portfolio to ensure a successful preclinical study and smooth transition to the clinical stage.

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Meet us at EASL 2025

Download Gubra’s EASL Posters

We are attending the EASL Congress from May 7-10, 2025. You can download our posters and explore the clinical translatability of our GAN DIO-MASH model, as well as our other biopsy-confirmed models for MASH and MASH-driven HCC.

Reproducible hepatoprotective effects and clinical translatability of semaglutide in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH
Abstract no: FRI-414
Presentation: 2025-5-9
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Hepatoprotective effects of efruxifermin in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH
Abstract no: FRI-370
Presentation: 2025-5-9
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Hepatoprotective effects of the oral fatty acid synthase inhibitor TVB-3664 in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH

Abstract no: FRI-413
Presentation: 2025-5-9

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Comparative anti-fibrotic efficacy of resmetirom, semaglutide, tirzepatide and efruxifermin in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH
Abstract no: FRI-383
Presentation: 2025-5-9
Download

Standard Study Outlines

1. GAN DIO-MASH mouse model

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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2. GAN DIO-MASH-HCC mouse model

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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5. CDAA-HFD mouse​ model

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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3. GAN ob/ob-MASH mouse model (prophylactic)​

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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4. GAN ob/ob-MASH mouse model (therapeutic)​

All study design can be customized to your research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

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We are experts in bridging preclinical and clinical development.

MICHAEL FEIGH Vice President, Scientific Sales

Michael’s primary focus is on MASH, MASH-HCC, obesity and idiopathic pulmonary fibrosis (IPF). Michael provides customers with scientific expertise in metabolic and fibrotic diseases, and knowhow for the preclinical evaluation of drug candidates from discovery to IND-enabling.

Let’s meet at EASL 2025

Contact us

Gubra

Hørsholm Kongevej 11B 2970 Hørsholm Denmark +45 3152 ­2650

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