New insights into disease progression and human translatability of the GAN DIO-NASH mouse
Join preclinical NASH experts Michael Feigh and Henrik Björk Hansen in a scientist-to-scientist talk about the latest research discoveries and advances within human translational models of non-alcoholic steatohepatitis (NASH).
Preclinical drug discovery in NASH – Narrowing the translational gap
In this webinar Principal Scientist at Gubra Henrik Björk Hansen discusses strategies to improve clinical translatability of preclinical models of NASH. The webinar introduces a diet-induced obese and biopsy-confirmed rodent model of NASH with progressive development of fibrosis and hepatocellular carcinoma, that recapitulates…
Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH
Clinical and Translational Science 15(5):1167-1186, 2022
Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis
BMC Gastroenterology 20:210, 2020
Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source
World Journal of Gastroenterology 25(33):4904-4920, 2019