Skip to content
Poster

An Unbiased and Automated Approach: AI-based Pipeline for Glomerulosclerosis Scoring in Rodent Models of Chronic Kidney Disease (CKD)

Background & Aim:

Glomerulosclerosis is a hallmark of chronic kidney disease (CKD) and involves the formation of glomerular scar tissue. Accurate histopathological evaluation of glomerulosclerosis is crucial for assessing the diagnosis, prognosis and treatment CKD patients. Several rodent models of CKD shows glomerulosclerosis and are highly instrumental in preclinical target discovery and drug development. To accelerate the objective and efficient assessment of glomerulosclerosis, we have designed, validated and implemented an AI-powered histopathological scoring system applicable for both mouse and rat models of CKD.

Subjects
Anti-GBM glomerulonephritis mouseChronic kidney diseaseReninAAV UNx db/db mouseMouseChronic kidney disease5/6 nephrectomy (Nx) ratRatHistopathology scoreImage analysis

For further information

Contact us

Gubra

Hørsholm Kongevej 11B
2970 Hørsholm
Denmark

+45 3152 ­2650

Back To Top