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Tailored study design & rapid initiation

Advance preclinical obesity candidates with speed and certainty

Gubra has extensive experience with diet-induced obese (DIO) animals and has successfully profiled numerous anti-obesity drug candidates in these translational models. Our preclinical CRO services include efficacy and mode-of-action studies on weight loss drugs, utilizing state-of-the-art in vivo, biochemical, histological and NGS technologies.

Explore our 2026 American Diabetes Association (ADA) Scientific Sessions data

Download Gubra’s ADA 2026 Posters


Download the latest research and explore how we can help accelerate the development of your preclinical drug candidate with conclusive data on weight loss efficacy and mode-of-action.

Discover more from our anti-obesity research

Related Publications


Standard Obesity & Diabetes Study Outline

Diet-Induced Obesity (DIO) Mouse Model

Preclinical Research Models of Obesity

All study design can be customized to your specific research needs. Contact us for a free consultation to get your customized study outline, quotation as well as expert advice on how to progress your study.

Use whole brain c-Fos imaging to understand your obesity compound’s effects in the CNS

Quantify the totalnumber of activatedneurons Statistical maps ofneural responses Get anatomicalannotation of activityin the entire brain Overlay withbenchmark maps fromalready approved drugs

PROGRESS YOUR STUDY WITH GREATER CERTAINTY​

High-resolution 3D whole-hindlimb imaging for quantitative muscle endpoints

Drug development for sarcopenic obesity requires multidimensional assessment of muscle structure, mass, and function. Gubra’s 3D imaging platform enables automated quantification of multiple histological endpoints in intact rodent hind limbs, integrated with in vivo metabolic and functional data to deliver robust, data-driven insights for your drug candidate.

 

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We are experts in bridging preclinical and clinical drug development.


Preclinical Research Models of Obesity

MARCO TOZZI Principal Scientist

Marco has a strong background within preclinical obesity and diabetes research. Reach out to Marco to get valuable scientific guidance in the design and execution of preclinical obesity/diabetes studies and how to optimally profile anti-obesity/diabetes drugs.

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Contact us

Gubra

Hørsholm Kongevej 11B
2970 Hørsholm
Denmark

+45 3152 ­2650

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