HØRSHOLM, Denmark – 20 September, 2021
Gubra ApS announced today a new research collaboration and license agreement with Bayer AG for the development of novel peptide therapeutics to treat cardiorenal disease.
Cardiorenal disease is an umbrella term for acute and chronic disorders, involving both the heart and the kidney.
Gubra to receive an upfront payment and potential future development and commercialization milestones of up to € 216 million.
Gubra announced the signing of a research collaboration and license agreement with Bayer AG for the development of novel peptide therapeutics to treat cardiorenal diseases. The collaboration utilizes Gubra’s machine learning-based peptide drug discovery platform (streaMLine) for fast screening and identification of potent therapeutic peptide candidates.
The joint research program between Gubra and Bayer AG aims at further maturing a novel therapeutic peptide for the potential treatment of cardiorenal disease. Cardiorenal disease is an umbrella term for acute and chronic disorders involving both the heart and the kidney. These disorders are associated with a high morbidity and mortality globally and currently available treatments are not optimal for all patients. Consequently, cardiorenal diseases cause a significant burden on health care systems around the world.
The collaboration will combine Gubra’s unique peptide drug discovery capabilities and use of advanced technologies with Bayer AG’s expertise in development of innovative medicines. The extensive experience in both companies with drug profiling in preclinical translational disease models also form an essential part of the collaboration.
“We are very pleased to enter this research collaboration and license agreement with Bayer,” said Henrik Blou, CEO of Gubra. “We have used streaMLine, our proprietary machine learning-based target and peptide drug discovery platform, to conceive this promising program currently undergoing preclinical maturation. We are pleased that the potential of our technology is being recognized by such a qualified partner capable of advancing innovative medicines into the clinic.”
Under the terms of the agreement, Gubra to receive an upfront payment and potential future development and commercialization milestones of up to € 216 million.
Sofia Pitt Boserup
Lead Communication Partner
Gubra is a privately held biotech company since 2008, headquartered in Denmark. The company is a science and technology driven company with two primary areas of business: Preclinical contract research services (CRO) and proprietary early target and drug discovery programs. Gubra’s primary focus is within the metabolic space (obesity, diabetes, NASH, CKD, CVD and diabetic complications) adding to this fibrotic disease areas such as IPF and IBD. Gubra specializes in in vivo pharmacology, peptide chemistry, molecular pharmacology, histology, 3D imaging, stereology, NGS (next generation sequencing), bioinformatics and ex vivo assays. High quality, scientific excellence, advanced digitalization, speed and solid teamwork, are key company traits which have established Gubra as a highly professional and competent partner in the market. Learn more at www.gubra.dk
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