Publication

Long-term treatment with liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has no effect on β-amyloid plaque load in two transgenic APP/PS1 mouse models of Alzheimer’s disease

PLOS One 11(7):e0158205, 2016

Hansen HH, Fabricius K, Barkholt P, Kongsbak-Wismann P, Schlumberger C, Jelsing J, Terwel D, Termont A, Pyke C, Knudsen LB, Vrang N.

Subjects

Alzheimer's disease Alzheimer's disease models Therapeutic Area Target Mouse Compound Method/Endpoint Species GLP-1 receptor Neurobehavior Liraglutide Stereology

Share this page

Resource Library

Related resources

Whole-brain 3D imaging for quantification of drug targets and treatment effects in mouse models of neurodegenerative diseases

Whole organ staining and 3D light sheet imaging for pharmacological research

Capillary, venous, and arterial vasculature 3D light sheet imaging and AI analysis in intact mouse organs

Transferrin receptor binding BBB-shuttle facilitates brain delivery of a therapeutic Aβ-antibody: A mouse whole-brain 3D light sheet imaging study

For further information

Contact us

Gubra

Hørsholm Kongevej 11B
2970 Hørsholm
Denmark

+45 3152 2650