Publications

Tap into Gubra’s vast production of publications and posters to get the latest knowledge and insights within our focus areas: diabetes, obesity, NASH and gastrointestinal diseases.

Gubra poster: Body-weight lowering agents and their comparative metabolic and hepatic effects in obese mouse models of non-alcoholic fatty liver disease and steatohepatitis

Jacob Jelsing, Michael Feigh, Kirstine Sloth Tølbøl, Sanne Skovgård Veidal, and Niels Vrang

Stereological assessment of pancreatic beta-cell mass development in male Zucker Diabetic Fatty (ZDF) rats: correlation with pancreatic beta-cell function

Paulsen SJ, Vrang N, Larsen LK, Larsen PJ, Jelsing J.

Effects of liraglutide and sibutramine on food intake, palatability, body weight and glucose tolerance in the gubra DIO-rats

Hansen G, Jelsing J, Vrang N.

The DPP4 inhibitor linagliptin delays the onset of diabetes and preserves β-cell mass in non-obese diabetic mice

Jelsing J, Vrang N, van Witteloostuijn SB, Mark M, Klein T.

Novel insight into the distribution of L-cells in the rat intestinal tract

Hansen CF, Vrang N, Sangild PT, Jelsing J.

Hypertrophy dependent doubling of L-cells in Roux-en-Y gastric bypass operated rats

Hansen CF, Bueter M, Theis N, Lutz T, Paulsen S, Dalbøge LS, Vrang N, Jelsing J.

Characterisation of age-dependent beta cell dynamics in the male db/db mice

Dalbøge LS, Almholt DL, Neerup TS, Vassiliadis E, Vrang N, Pedersen L, Fosgerau K, Jelsing J.

Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion

Paulsen SJ, Larsen LK, Hansen G, Chelur S, Larsen PJ, Vrang N.

The novel GLP-1-gastrin dual agonist ZP3022 improves glucose homeostasis and increases β-cell mass without affecting islet number in db/db mice

Dalbøge LS, Almholt DL, Neerup TS, Vrang N, Jelsing J, Fosgerau K.

The sodium glucose cotransporter type 2 inhibitor empagliflozin preserves β-cell mass and restores glucose homeostasis in the male zucker diabetic fatty rat

Hansen HH, Jelsing J, Hansen CF, Hansen G, Vrang N, Mark M, Klein T, Mayoux E.

The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss

Secher A, Jelsing J, Baquero AF, Hecksher-Sørensen J, Cowley MA, Dalbøge LS, Hansen G, Grove KL, Pyke C, Raun K, Schäffer L, Tang-Christensen M, Verma S, Witgen BM, Vrang N, Bjerre Knudsen L.

Expression and Distribution of Glucagon-Like Peptide-1 Receptor mRNA, Protein and Binding in the Male Nonhuman Primate (Macaca mulatta) Brain

Heppner KM, Kirigiti M, Secher A, Paulsen SJ, Buckingham R, Pyke C, Knudsen LB, Vrang N, Grove KL.

The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer's Disease

Hansen HH, Fabricius K, Barkholt P, Niehoff ML, Morley JE, Jelsing J, Pyke C, Knudsen LB, Farr SA, Vrang N.

A Hamster Model of Diet-Induced Obesity for Preclinical Evaluation of Anti-Obesity, Anti-Diabetic and Lipid Modulating Agents

Dalbøge LS, Pedersen PJ, Hansen G, Fabricius K, Hansen HB, Jelsing J, Vrang N.

The IL-1β Receptor Antagonist SER140 Postpones the Onset of Diabetes in Female Nonobese Diabetic Mice

Cucak H, Hansen G, Vrang N, Skarsfeldt T, Steiness E, Jelsing J.

Alterations in hypothalamic gene expression following Roux-en-Y gastric bypass

Barkholt P, Pedersen PJ, Hay-Schmidt A, Jelsing J, Hansen HH, Vrang N.

Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer’s Disease

Hansen HH, Fabricius K, Barkholt P, Kongsbak-Wismann P, Schlumberger C, Jelsing J, Terwel D, Termont A, Pyke C, Knudsen LB, Vrang N.

The endogenous preproglucagon system is not essential for gut growth homeostasis in mice

Wismann P, Barkholt P, Secher T, Vrang N, Hansen HB, Jeppesen PB, Baggio LL, Koehler JA, Drucker DJ, Sandoval DA, Jelsing J.

Mouse models of nonalcoholic steatohepatitis in preclinical drug development

Hansen HH, Feigh M, Veidal SS, Rigbolt KT, Vrang N, Fosgerau K.

Neuromedin U inhibits food intake partly by inhibiting gastric emptying. Peptides.

Dalbøge LS, Pedersen SL, Secher T, Holst B, Vrang N, Jelsing J.

Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy

Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Kristoffer Tobias Gustav Rigbolt, Kirstine Sloth Tølbøl, Jacob Jelsing, Niels Vrang, Michael Feigh