Publication

Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy

Scientific Reports 10:16130, 2020

Thisted L, Østergaard MV, Pedersen AA, Pedersen PJ, Lindsay RT, Murray AJ, Fink LN, Pedersen TX, Secher T, Johansen TT, Thrane ST, Skarsfeldt T, Jelsing J, Thomsen MB, Zois NE

Subjects
Therapeutic AreaCardiovascular disease (CVD)Chronic kidney disease (CKD)Beta-cell massMethod/EndpointIsoprenaline-induced cardiomyopathyDiabetesSpeciesDiabetic cardiomyopathyBody weightRatBlood biochemistryDiabetic kidney disease (DKD)BioinformaticsEchocardiography (ECG)Glomerular filtration rate (GFR)Image analysisImmunohistochemistryKidney morphometryNephrectomyPancreatectomyRNA sequencingSurgeryUrine biochemistry

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