Mode of action studies Hyperinsulinaemic euglycaemic clamp Glucose infusion rate during hyperinsulinaemic euglycaemic clamp in lean and male Gubra DIO rats. Data demonstrates a reduced insulin sensivity in Gubra DIO rats compared to lean animals, and improved insulin...
Chronic efficacy studies Longterm effects on glucose homeostasis in ZDF rats Data demonstrating the efficacy of 8 weeks chronic treatment with the DPP-4i (linagliptin), SGLT-2i (dapagliflozin), GLP-1 (liraglutide) and SUR (glibenclamide) on OGTT insulin and glucose...
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