Publication

Neurturin and a GLP-1 analogue act synergistically to alleviate diabetes in Zucker diabetic fatty rats

Diabetes 66(7):2007–2018, 2017

Trevaskis JL, Sacramento CB, Jouihan H, Ali S, Le Lay J, Oldham S, Bhagroo N, Boland BB, Cann J, Chang Y, O’Day T, Howard V, Reers C, Winzell MS, Smith DM, Feigh M, Barkholt P, Schreiter K, Austen M, Andag U, Thompson S, Jermutus L, Coghlan MP, Grimsby J, Dohrmann C, Rhodes CJ, Rondinone CM, Sharma A

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Subjects

Disease model Therapeutic Area Target ZDF rat Compound Method/Endpoint Diabetes models Diabetes c-Fos activation Obesity GLP-1 receptor Oral glucose tolerance test (OGTT)Liraglutide Neurturin

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