Publication

Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis

BMC Gastroenterology 20:210, 2020

Hansen HH, Ægidius HM, Oró D, Evers S, Heebøll S, Eriksen PL, Bengtsson A, Veidal SS, Feigh M, Knop FK, Grønbæk H, Miranda D, Trevaskis JL, Vrang N, Jelsing J, Rigbolt KTG

Subjects
GAN DIO-NASH (GAN DIO-MASH) mouseTherapeutic AreaHumanMouseMethod/EndpointSpeciesBody compositionBody weightBlood biochemistryBioinformaticsNon-alcoholic steatohepatitis/Metabolic dysfunction-associated steatohepatitis (NASH/MASH)Histopathology scoreIntraperitoneal glucose tolerance test (IPGTT)Image analysisImmunohistochemistryLiver biopsyLiver morphometryRNA sequencing

Share this page

Resource Library

Related resources
Poster
Metabolic, biochemical and histological effects of INT-767 in the GAN diet-induced and biopsy-confirmed ob/ob mouse model of NASH
Publication
Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis
Publication
Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis
Publication
Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH

For further information

Contact us

Gubra

Hørsholm Kongevej 11B
2970 Hørsholm
Denmark

+45 3152 ­2650

Back To Top