Publication
Activation of adenosine monophosphate-activated protein kinase reduces the onset of diet-induced hepatocellular carcinoma in mice
Hepatology Communications 4(7):1056-1072, 2020
Schmoll D, Ziegler N, Viollet B, Foretz M, Even PC, Azzout-Marniche D, Madsen AN, Illemann M, Egebjerg KM, Feigh M, Czech J, Glombik H, Olsen JA, Hennerici W, Steinmeyer K, Elvert R, Castañeda TR, Kannt A
Therapeutic AreaGAN DIO-NASH-HCC (GAN DIO-MASH-HCC) mouseMouseTargetob/ob mouseMethod/EndpointSpeciesAMPKAMLN ob/ob-NASH (AMLN ob/ob-MASH) mouseBody weightBlood biochemistryHepatocellular carcinoma (HCC)Non-alcoholic steatohepatitis/Metabolic dysfunction-associated steatohepatitis (NASH/MASH)Histopathology scoreImage analysisImmunohistochemistryLiver biopsyLiver morphometryReal-time food intake/activity analysis
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