Ex vivo assays
Customized pre-clinical assay data packages
Get confidence in your study endpoints by tapping into our extensive experience with ex vivo biochemical and immuno-assays combined with broad model knowledge ensuring reproducible pre-clinical assay data packages.
Solutions are custom-made to meet your specific needs using a variety of tissues, blood, urine or stool from your internal experiments or from in vivo studies performed at Gubra.
- Cobas c501 clinical assays
- Colorimetric assays
- MSD multiplex
- Time-resolved FRET
- Flow cytometry
- Biomek FX liquid/sample handling
- FluidX barcoded tube handling
- Pharmacokinetics (PK)
- Assay development (proteins/phosphoproteins)
- Scientific and technological evaluation of suggested biomarkers
- Pre-test in model-relevant matrices for valid and reproducible results
Flow cytometry services
Mapping out drug effects on inflammatory cells
Our flow cytometry services can be customized to meet your needs and applied in a broad range of tissues and disease indications. Applications include immune phenotyping, population dynamics and target engament assays.
We have developed a high throughput method for mapping out hepatic immune cell population in our pre-clinical models of NASH.
GLP-1 (active and total)
- Cystatin C
Obesity and dyslipidaemia
Cholesterol (total, HDL, LDL)
Free fatty acids
TNF-α, IL-6, IL-1β
KC/GRO (CXCL1), MIP-2 (CXCL2)
IP-10, IL-10, IL-5
Oxidative stress (TBARS, 4-HNE, 8-OHdG)
- AST, ALT, ALP
- Total bile acids
- Cytokeratin 18
- Hyaluronic acid